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Collagens: The Fence Boards
Your horse's built-in structural support system Every tendon, every ligament, every joint — held together by the same protein that makes a well-built fence stand straight through years of weather and load. Here's what collagen actually does, and why it's the first thing we talk about. THE ANALOGY Think of collagen like your arena's fence boards. A well-built fence doesn't flex when a horse leans into it, doesn't rot under pressure, and doesn't need replacing every season. Tha
Apr 272 min read


A Second Chance: Vivi’s Story of Resilience, Injury, and Return to Ride
Before the ribbons, before the results — there are stories like this one. Stories that remind us why we do what we do. Meet Vivi: More Than a Horse For Emma, dressage rider and founder of Emma Claire Collective, Vivi isn’t just a horse. He’s her heart horse. Vivi (Du Velv), a 21-year-old Dutch Warmblood, has been by Emma’s side for nearly a decade. Their partnership is built on years of trust, growth, and resilience — but also marked by a long history of setbacks. From multip
Apr 233 min read


Case 2: Managing Grade 4 LF Lameness with Tendon Injury and Structured Rehabilitation
Overview This case highlights the progression and management of a severe left forelimb (LF) soft tissue injury in a performance horse presenting with acute lameness and a history of prior ligament intervention. The horse presented with: Grade 4 LF lameness DDF tendon tear and associated tendonitis Prior annular ligament resection Ultrasound findings of fibrosis with evidence of a new tear This combination of prior surgical alteration, active soft tissue injury, and structural
Apr 223 min read


Case 1: Managing Advanced RF Injury with Surgical History and Biologic Support
Day 0 Moderate Grade 3 RF- Blocked to Foot Overview This case highlights the progression and management of a complex right forelimb (RF) pathology in a performance horse with a significant surgical history. The horse presented with: Moderate Grade 3 RF lameness, localized to the foot Radiographic evidence of coffin joint osteoarthritis (OA) Prior surgical fusion of the distal interphalangeal joint (DIT) and tarsometatarsal (TMT) joints in the left hind (LH) This combination
Apr 222 min read


The Biologic Breakdown: In Vitro Characterization of Equine UC Allograft
To characterize the protein composition and cytokine profile of a cryopreserved, microparticulate equine umbilical cord (UC) allograft using mass spectrometry (MS) and enzyme-linked immunosorbent assay (ELISA). Methods Sample Preparation UC tissue was harvested from 11 single-source, healthy equine donors. Cryopreserved at −80 °C and processed into microparticulate suspension. A total of 13 samples were analyzed. Proteomic Analysis: High-resolution tandem mass spectrometr
Apr 142 min read


Paving the Way: Defining Safety, Consistency & Clinical Readiness in Equine Biologics
The following is a summary of the Article “Cryopreserved equine umbilical cord tissue allograft characterization and biocompatibility in vivo in musculoskeletal tissues: a controlled study” that was originally published in BMC Medicine, 2025 authored by Bertone et al. 1 Background: Musculoskeletal (MSK) injuries are prevalent in equine and human athletes. Biologic tissue allografts, particularly from the umbilical cord (UC), offer potential for MSK tissue repair. However, c
Jan 132 min read


The Safety Standard: Evaluating Cryopreserved Equine UC Allografts
This summary highlights the robust safety profile of a cryopreserved equine umbilical cord allograft, as demonstrated through three comprehensive in vivo studies published in “Cryopreserved equine umbilical cord tissue allograft characterization and biocompatibility in vivo in musculoskeletal tissues: a controlled study.” BMC Medicine, 2025.1 Study Overview Three in vivo studies evaluated safety and biocompatibility of cryopreserved equine umbilical cord (UC) allograft. Foc
Oct 1, 20252 min read


The Consistency Code: Evaluating Protein & Cytokine Uniformity in Equine UC Allografts
This summary document highlights the lot-to-lot consistency of a cryopreserved equine umbilical cord (UC) allograft; equicenta™ CTM, as demonstrated through proteomic and cytokine analyses across multiple donors and batches. These results were first published in Bertone AL et al. “Cryopreserved equine umbilical cord tissue allograft characterization and biocompatibility in vivo in musculoskeletal tissues: a controlled study.” BMC Medicine, 2025 Study Overview Objective: To e
Aug 8, 20252 min read
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